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WNT9A Antibody (MA5-24050) in WB
Western blot analysis of WNT9A in KATO-III human gastric carcinoma cell line and ME‚180 human cervical epithelial carcinoma cell line. Samples were incubated in WNT9A monoclonal antibody (Product # MA5-24050) using a dilution of 5 µg/mL followed by a HRP-conjugated Anti-Mouse IgG secondary antibody. Specific bands for native Wnt-9a were detected at approximately 30 kDa (as indicated). This experiment was conducted under reducing conditions.
产品信息
MA5-24050
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
326711
抗原
E. coli-derived recombinant human Wnt-9a Pro48-Glu92 and Arg231-Phe304
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2610413
产品详细信息
In direct ELISAs, no cross-reactivity with recombinant human Wnt-2, -3a, -6, -7a, -7b, recombinant mouse Wnt-1, -2b, -4, -5a, -5b, -8a, -8b, -9b, -10a, -10b, -11, or -16 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
WNT9A is a ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. WNT9A is likely to signal over only few cell diameters.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC138165; MGC141991; Protein Wnt-14; Protein Wnt-9a; wingless-type MMTV integration site family member 9A; wingless-type MMTV integration site family, member 14; wingless-type MMTV integration site family, member 9A
基因别名: WNT14; WNT9A
UniProt ID: (Human) O14904
Entrez Gene ID: (Human) 7483
mitotic cell cycle checkpoint
cell-cell signaling
multicellular organism development
negative regulation of cell proliferation
Wnt signaling pathway
neuron differentiation
negative regulation of chondrocyte differentiation
embryonic forelimb morphogenesis
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
cell fate commitment
positive regulation of cell differentiation
positive regulation of smoothened signaling pathway
embryonic skeletal system morphogenesis
canonical Wnt signaling pathway
iris morphogenesis
cornea development in camera-type eye
cellular response to retinoic acid
embryonic skeletal joint development
