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WWC2 Antibody (PA5-71284) in WB
Journal of oncology 2022 -
Figure 3 miR-146a-5p downregulates WWC2 to activate the Hippo-YAP signaling pathway. (a) The Venn map of the intersection of target genes obtained from the TargetScan, miRWalk, miRDB, and ENCORI databases and differentially expressed genes in GEPIA2 database in cervical cancer. (b) Analysis of the expression of WWC2 in cervical cancer by GEPIA2 database. Red represents cervical cancer samples, and gray repr... View More
产品信息
PA5-71284
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the C-terminal region of human WWC2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2691041
产品详细信息
This target displays homology in the following species: Cow: 92%; Dog: 100%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 92%; Yeast: 83%
靶标信息
This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-terminal alpha protein kinase C binding sites and class III PDZ domain-interaction motifs. Proteins of this family are able to form homo- and heterodimers and to modulate hippo pathway signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BH-3-only member B; BH3-only member B protein; Protein WWC2; WW domain-containing protein 2; WW, C2 and coiled-coil domain containing 2
基因别名: BOMB; WWC2
UniProt ID: (Human) Q6AWC2
Entrez Gene ID: (Human) 80014
