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WWP1 Antibody (A302-950A) in IP
Detection of human WWP1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-WWP1 antibody (Product # A302-950A) used for IP at 3 µg/mg lysate. WWP1 was also immunoprecipitated by rabbit anti-WWP1 antibody A302-949A, which recognizes an upstream epitope. For blotting immunoprecipitated WWP1, A302-949A was used at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 10 seconds.
产品信息
A302-950A
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 300 and 350 of Human WW Domain Containing E3 Ubiquitin Protein Ligase 1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AIP5; atrophin-1 interacting protein 5; Atrophin-1-interacting protein 5; DKFZp434D2111; HECT-type E3 ubiquitin transferase WWP1; Nedd-4-like ubiquitin-protein ligase; NEDD4-like E3 ubiquitin-protein ligase WWP1; TGIF-interacting ubiquitin ligase 1; Tiul1; WW domain-containing protein 1
基因别名: AIP5; hSDRP1; Tiul1; WWP1
UniProt ID: (Human) Q9H0M0
Entrez Gene ID: (Human) 11059
signal transduction
central nervous system development
protein ubiquitination
ion transmembrane transport
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of transcription, DNA-templated
viral entry into host cell
