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WWP1 Antibody (PA5-36008) in IHC (P)
WWP1 Polyclonal Antibody detects WWP1 protein at cytosol on mouse stomach by immunohistochemical analysis. Sample: Paraffin-embedded mouse stomach. WWP1 Polyclonal Antibody (Product # PA5-36008) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-36008
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 492 and 774 of WWP1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2553318
产品详细信息
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Predicted reactivity: Mouse (99%), Rat (99%), Chicken (96%), Rhesus Monkey (99%), Bovine (99%).
靶标信息
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AIP5; atrophin-1 interacting protein 5; Atrophin-1-interacting protein 5; DKFZp434D2111; HECT-type E3 ubiquitin transferase WWP1; Nedd-4-like ubiquitin-protein ligase; NEDD4-like E3 ubiquitin-protein ligase WWP1; TGIF-interacting ubiquitin ligase 1; Tiul1; WW domain-containing protein 1
基因别名: 8030445B08Rik; AIP5; hSDRP1; SDRP1; Tiul1; WWP1
UniProt ID: (Human) Q9H0M0, (Mouse) Q8BZZ3
Entrez Gene ID: (Human) 11059, (Mouse) 107568
ubiquitin-protein transferase activity
protein binding
ligase activity
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
signal transduction
central nervous system development
protein ubiquitination
ion transmembrane transport
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of transcription, DNA-templated
viral entry into host cell
T cell differentiation
lung development
