Invitrogen

XCL1/XCL2 Polyclonal Antibody

查看其他2个XCL1/XCL2抗体

抗体检测数据 (1)

XCL1/XCL2 Antibody in Western Blot (WB)

XCL1/XCL2 Antibody in Western Blot (WB)

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XCL1/XCL2 Antibody (PA5-75840) in WB

Western blot analysis of XCL1/XCL2 in Lane 1: HEK293T whole cell lysate, Lane 2: RAW264.7 whole cell lysate Lane 3: H9C2 whole cell lysate. Samples were incubated with XCL1/XCL2 polyclonal antibody (Product # PA5-75840) at a dilution of 1:500.

XCL1/XCL2 Antibody in Western Blot (WB)

Product Image Gallery

XCL1/XCL2 Antibody in Western Blot (WB) — Western blot analysis of XCL1/XCL2 in Lane 1: HEK293T whole cell lysate, Lane 2: RAW264.7 whole cell lysate Lane 3: H9C2 whole cell lysate. Samples were incubated with XCL1/XCL2 polyclonal antibody (Product # PA5-75840) at a dilution of 1:500.

产品信息

PA5-75840

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to residues in Human XCL1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2719568

产品详细信息

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

靶标信息

Lymphotactin, otherwise known as XCL1, is a member of the C-chemokine family that uniquely acts as a chemoattractant for lymphocytes, but not monocytes or neutrophils, suggesting an important regulatory role in lymphocyte trafficking and inflammation. Lymphotactin, shown to signal through chemokine XC receptor 1 (XCR1), is detected at the highest level in the spleen and at low levels in the lungs, small intestine and colon, and is abundantly and selectively expressed by activated T cells, in particular CD8+ T cells, and is also produced by NK cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ATAC; C motif chemokine 1; C motif chemokine 2; chemokine (C motif) ligand 1; chemokine (C motif) ligand 2; Cytokine SCM-1; Cytokine SCM-1 beta; Lymphotactin; Lymphotaxin; SCM-1-alpha; single cysteine motif 1a; small inducible cytokine subfamily C, member 1 (lymphotactin); small inducible cytokine subfamily C, member 2; Small-inducible cytokine C1; XC chemokine ligand 1; XC chemokine ligand 2

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基因别名: AI661682; ATAC; LPTN; LTN; SCM-1; SCM-1a; SCM-1b; SCM1; SCM1A; SCM1B; SCYC1; SCYC2; XCL1; XCL2

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UniProt ID: (Human) P47992, (Human) Q9UBD3, (Rat) P51672, (Mouse) P47993

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Entrez Gene ID: (Human) 6375, (Human) 6846, (Rat) 171371, (Mouse) 16963

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chemokine activity chemokine receptor binding protein homodimerization activity CCR chemokine receptor binding protein binding cytokine activity cytokine intercellular signal molecule

positive regulation of T cell mediated cytotoxicity monocyte chemotaxis positive regulation of leukocyte chemotaxis negative regulation of T cell cytokine production positive regulation of T cell cytokine production negative regulation of T-helper 1 type immune response signal transduction G-protein coupled receptor signaling pathway cell-cell signaling response to virus positive regulation of T cell chemotaxis neutrophil chemotaxis negative regulation of interferon-gamma production negative regulation of interleukin-2 production positive regulation of interleukin-10 production mature natural killer cell chemotaxis negative regulation of sequence-specific DNA binding transcription factor activity positive regulation of GTPase activity negative regulation of transcription, DNA-templated regulation of inflammatory response positive regulation of inflammatory response release of sequestered calcium ion into cytosol positive regulation of release of sequestered calcium ion into cytosol chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to interleukin-4 cellular response to tumor necrosis factor cellular response to transforming growth factor beta stimulus positive regulation of transforming growth factor beta production positive regulation of granzyme B production positive regulation of neutrophil chemotaxis positive regulation of thymocyte migration positive regulation of natural killer cell chemotaxis positive regulation of granzyme A production negative regulation of T-helper 1 cell activation positive regulation of B cell chemotaxis positive regulation of T-helper 2 cell cytokine production positive regulation of T-helper 1 cell cytokine production positive regulation of immunoglobulin production in mucosal tissue negative regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of CD8-positive, alpha-beta T cell proliferation inflammatory response blood circulation lymphocyte chemotaxis chemotaxis immune response cell chemotaxis positive regulation of immune response to tumor cell positive regulation of innate immune response