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XIAP Antibody (MA5-49156) in WB
Western blot analysis of XIAP using XIAP antibody (Product # MA5-49156). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human Hela whole cell lysates; Lane 2: human MCF-7 whole cell lysates; Lane 3: human PANC-1 whole cell lysates; Lane 4: human U87 whole cell lysates; Lane 5: rat heart tissue lysates; Lane 6: rat testis tissue lysates; Lane 7: mouse heart tissue lysates; Lane 8: ... View More
产品信息
MA5-49156
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3G2G1
抗原
E.coli-derived human XIAP recombinant protein (Position: A15-V244).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3074814
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Human XIAP shares 89.4% and 90.7% amino acid (aa) sequence identity with mouse and rat XIAP, respectively.
靶标信息
ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP+ phosphate to ATP. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits. While the F0 consists of a, b, and c subunits.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apoptosis inhibitor protein 3; baculoviral IAP repeat-containing 4; Baculoviral IAP repeat-containing protein 4; BIR4; E3 ubiquitin-protein ligase XIAP; HILP; IAP homolog A; IAP-3; IAP-like protein; ILP; Inhibitor of apoptosis protein 3; RIAP-3; RING-type E3 ubiquitin transferase XIAP; RP1-315G1.5; X-linked IAP; X-linked inhibitor of apoptosis protein; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
基因别名: 1110015C02Rik; Aipa; API3; BIRC4; hIAP-3; hIAP3; IAP-3; IAP3; ILP-1; ILP1; MIHA; riap3; XIAP; XLP2
UniProt ID: (Human) P98170, (Rat) Q9R0I6, (Mouse) Q60989
Entrez Gene ID: (Human) 331, (Rat) 63879, (Mouse) 11798
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
identical protein binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
ubiquitin protein ligase activity
protease binding
scaffold protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
protease inhibitor
apoptotic process
cellular response to DNA damage stimulus
Wnt signaling pathway
protein ubiquitination
regulation of BMP signaling pathway
positive regulation of protein ubiquitination
regulation of cell proliferation
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of innate immune response
regulation of inflammatory response
copper ion homeostasis
regulation of nucleotide-binding oligomerization domain containing signaling pathway
positive regulation of canonical Wnt signaling pathway
mitotic spindle assembly
positive regulation of protein linear polyubiquitination
inhibition of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of neuron apoptotic process
neuron apoptotic process
