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XRCC2 Antibody (PA5-95935) in IHC (P)
Immunohistochemistry analysis of XRCC2 in paraffin-embedded mouse spinal cord. Samples were incubated with XRCC2 Polyclonal antibody (Product # PA5-95935) using a dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-95935
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of human XRCC2 (NP_0054221)
偶联物
形式
Liquid
浓度
2.03 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2807737
产品详细信息
Immunogen sequence: MCSAFHRAES GTELLARLEG RSSLKEIEPN LFADEDSPVH GDILEFHGPE GTGKTEMLYH LTARCILPKS EGGLEVEVLF IDT
Positive Samples: Mouse testis; Cellular Location: Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center
靶标信息
The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad5. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp781P0919; DNA repair protein XRCC2; recA/RAD51 family protein; X-ray repair complementing defective repair in Chinese hamster cells 2; X-ray repair cross complementing protein 2; X-ray repair cross-complementing protein 2
基因别名: 4921524O04Rik; 8030409M04Rik; FANCU; RAD51; RecA; RGD1564823; XRCC2
UniProt ID: (Human) O43543, (Mouse) Q9CX47
Entrez Gene ID: (Human) 7516, (Mouse) 57434, (Rat) 499966
mitotic cell cycle
meiotic DNA recombinase assembly
double-strand break repair via homologous recombination
DNA synthesis involved in DNA repair
strand displacement
in utero embryonic development
somitogenesis
DNA repair
mitotic recombination
meiotic nuclear division
reciprocal meiotic recombination
response to X-ray
response to ionizing radiation
response to gamma radiation
multicellular organism growth
strand invasion
negative regulation of neuron apoptotic process
positive regulation of neurogenesis
centrosome organization
regulation of fibroblast apoptotic process
DNA recombination
cellular response to DNA damage stimulus
neurogenesis
biological_process
