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XRCC6BP1 Antibody (H00091419-D01P) in WB
Western Blot analysis of XRCC6BP1 expression in transfected 293T cell line (H00091419-T02) by XRCC6BP1 MaxPab polyclonal antibody.
Lane 1: XRCC6BP1 transfected lysate(28.10 KDa).
Lane 2: Non-transfected lysate.
Lane 1: XRCC6BP1 transfected lysate(28.10 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00091419-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
XRCC6BP1 (NP_150592.1, 1 a.a. approximately 246 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MAGAPDERRR GPAAGEQLQQ QHVSCQVFPE RLAQGNPQQG FFSSFFTSNQ KCQLRLLKTL ETNPYVKLLL DAMKHSGCAV NKDRHFSCED CNGNVSGGFD ASTSQIVLCQ NNIHNQAHMN RVVTHELIHA FDHCRAHVDW FTNIRHLACS EVRAANLSGD CSLVNEIFRL HFGLKQHHQT CVRDRATLSI LAVRNISKEV AKKAVDEVFE SCFNDHEPFG RIPHNKTYAR YAHRDFENRD RYYSNI
靶标信息
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ku70 binding protein 3; Ku70-binding protein 3; Mitochondrial inner membrane protease ATP23 homolog; XRCC6 binding protein 1; XRCC6-binding protein 1
基因别名: ATP23; KUB3; XRCC6BP1
UniProt ID: (Human) Q9Y6H3
Entrez Gene ID: (Human) 91419
