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XTP4 Antibody (MA5-26355) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 10mM citric buffer, pH6.0, 100°C for 10min was used. Following antigen retrieval, tissues were probed with a C17orf37 monoclonal antibody (Product # MA5-26355).
产品信息
MA5-26355
产品规格
种属反应
Dog,
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI2D2
抗原
Full length human recombinant protein of C17orf37 produced in E.coli
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723791
靶标信息
During the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3' end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HBV X-transactivated gene 4 protein; HBV XAg-transactivated protein 4; MGC14832; Migration and invasion enhancer 1; protein C17orf37; protein C17orf37 homolog; Protein C35
基因别名: 1810046J19Rik; AI463380; C17orf37; C35; MIEN1; ORB3; RDX12; RGD1306682; XTP4
UniProt ID: (Human) Q9BRT3, (Mouse) Q9CQ86
Entrez Gene ID: (Dog) 480532, (Human) 84299, (Rat) 360617, (Mouse) 103742
