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Product Details
PA5-53883
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human YARS. Recombinant protein control fragment (Product #RP-92043).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2649715
Product Specific Information
Immunogen sequence: GNVENNGVLS FIKHVLFPLK SEFVILRDEK WGGNKTYTAY VDLEKDFAAE VVHPGDLKNS VEVALNKLLD PIREKFNTPA LKKLASAAYP DPSKQKPMAK GPAKNSEPEE VIPSRLDIRV GKIITVEKHP DAD
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 93%.
Target Information
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: tyrosine tRNA ligase 1, cytoplasmic; Tyrosine--tRNA ligase, cytoplasmic; tyrosyl trna synthetase; tyrosyl--tRNA ligase; Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase, cytoplasmic; TyrRS
Gene Aliases: AL024047; AU018965; CMTDIC; TYRRS; YARS; YARS1; YRS; YTS
UniProt ID: (Human) P54577, (Mouse) Q91WQ3, (Rat) Q4KM49
Entrez Gene ID: (Human) 8565, (Mouse) 107271, (Rat) 313047
tRNA binding
tyrosine-tRNA ligase activity
valine-tRNA ligase activity
signal transducer activity
interleukin-8 receptor binding
protein binding
ATP binding
poly(A) RNA binding
nucleotide binding
RNA binding
aminoacyl-tRNA ligase activity
ligase activity
isoleucine-tRNA ligase activity
translational protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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