Invitrogen

YOD1 Polyclonal Antibody

YOD1 Antibody in Immunocytochemistry (ICC/IF)

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YOD1 Antibody (PA5-35042) in ICC/IF

Immunocytochemistry analysis of YOD1 in WiDr cells. Samples were incubated in YOD1 polyclonal antibody (Product # PA5-35042) followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

YOD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

PA5-35042

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

- -

免疫组化 (IHC)

- -

免疫组化（石蜡） (IHC (P))

1:50-1:100

免疫细胞化学 (ICC/IF)

1:10-1:50

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 319-347 amino acids from the C-terminal region of human YOD1

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2552352

产品详细信息

This antibody is predicted to react with chicken and zebrafish based on sequence homology.

靶标信息

Deubiquitinating enzymes (DUBs) are proteases that specifically cleave ubiquitin linkages, negating the action of ubiquitin ligases. DUBA8 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DUBA-8; HIN-7; HIV-1-induced protease 7; hsHIN7; OTU domain containing 2; OTU domain-containing protein 2; Ubiquitin thioesterase OTU1; YOD1 OTU deubiquinating enzyme 1 homolog ( yeast)

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基因别名: DUBA8; HIN7; OTUD2; PRO0907; YOD1

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UniProt ID: (Human) Q5VVQ6

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Entrez Gene ID: (Human) 55432

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功能

thiol-dependent ubiquitin-specific protease activity protein binding ubiquitin protein ligase binding metal ion binding Lys63-specific deubiquitinase activity ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol Lys48-specific deubiquitinase activity cysteine protease

参与通路

ER-associated ubiquitin-dependent protein catabolic process endoplasmic reticulum unfolded protein response protein K29-linked deubiquitination protein K11-linked deubiquitination protein K63-linked deubiquitination protein K48-linked deubiquitination negative regulation of retrograde protein transport, ER to cytosol protein K27-linked deubiquitination protein K33-linked deubiquitination