Invitrogen

YOD1 Polyclonal Antibody

YOD1 Antibody in Immunocytochemistry (ICC/IF)

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YOD1 Antibody (PA5-55837) in ICC/IF

Immunofluorescent staining of YOD1 in human cell line A-431 using a YOD1 Polyclonal Antibody (Product # PA5-55837) shows localization to nucleoplasm, nuclear bodies and plasma membrane.

YOD1 Antibody in Immunohistochemistry (IHC)

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产品信息

PA5-55837

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:200-1:500

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human YOD1. Recombinant protein control fragment (Product #RP-94482).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2649734

产品详细信息

Immunogen sequence: DMLIIEEDQT RPRSSPAFTK RGASSYVRET LPVLTRTVVP ADNSCLFTSV YYVVEGGVLN PACAPEMRRL IAQIVA

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 91%.

靶标信息

Deubiquitinating enzymes (DUBs) are proteases that specifically cleave ubiquitin linkages, negating the action of ubiquitin ligases. DUBA8 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DUBA-8; HIN-7; HIV-1-induced protease 7; hsHIN7; OTU domain containing 2; OTU domain-containing protein 2; Ubiquitin thioesterase OTU1; YOD1 OTU deubiquinating enzyme 1 homolog ( yeast)

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基因别名: DUBA8; HIN7; OTUD2; PRO0907; YOD1

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UniProt ID: (Human) Q5VVQ6

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Entrez Gene ID: (Human) 55432

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功能

thiol-dependent ubiquitin-specific protease activity protein binding ubiquitin protein ligase binding metal ion binding Lys63-specific deubiquitinase activity ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol Lys48-specific deubiquitinase activity cysteine protease

参与通路

ER-associated ubiquitin-dependent protein catabolic process endoplasmic reticulum unfolded protein response protein K29-linked deubiquitination protein K11-linked deubiquitination protein K63-linked deubiquitination protein K48-linked deubiquitination negative regulation of retrograde protein transport, ER to cytosol protein K27-linked deubiquitination protein K33-linked deubiquitination