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YY1 Antibody (MA5-37631) in IHC (P)
Immunohistochemistry (Paraffin) analysis of YY1 in Zebra fish brain tissue sections using the YY1 Monoclonal Antibody (Product # MA5-37631) at a dilution of 1:25. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1:25) for 1 hours at 37°C. A undiluted... View More
产品信息
MA5-37631
产品规格
种属反应
Cynomolgus monkey,
Human,
Rat,
Zebrafish
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
1183CT6.5.23.6
抗原
purified His-tagged YY1 protein
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2897557
靶标信息
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Delta transcription factor; INO80 complex subunit S; NF-E1; transcription factor Yy1; Transcriptional repressor protein YY1; Yin and yang 1; Yin and Yang 1 protein; YY-1
基因别名: DELTA; fb59g10; INO80S; NF-E1; NMP-1; NMP1; UCRBP; wu:fa16g07; wu:fb59g10; YIN-YANG-1; YY1
UniProt ID: (Human) P25490
Entrez Gene ID: (Human) 7528, (Cynomolgus monkey) 102147204, (Rat) 24919, (Zebrafish) 322397
four-way junction DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
enhancer sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
transcription corepressor activity
RNA binding
protein binding
zinc ion binding
transcription regulatory region DNA binding
SMAD binding
histone deacetylase binding
sequence-specific DNA binding
metal ion binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
nucleic acid binding
C2H2 zinc finger transcription factor
negative regulation of transcription from RNA polymerase II promoter
double-strand break repair via homologous recombination
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
spermatogenesis
response to UV-C
negative regulation of gene expression
cell differentiation
cellular response to UV
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
RNA localization
anterior/posterior pattern specification
positive regulation of gene expression
response to prostaglandin F
positive regulation of transcription from RNA polymerase II promoter
camera-type eye morphogenesis
chromosome organization
cellular response to interleukin-1
angiogenesis
brain development
heart development
