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产品信息
PA5-103320
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ZBTB17(Accession Q13105), corresponding to amino acid residues V195-A245.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852665
产品详细信息
Antibody detects endogenous levels of total ZBTB17.
靶标信息
Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LP-1; Miz-1; Myc-interacting zinc finger protein 1; Myc-interacting Zn finger protein-1; Polyomavirus late initiator promoter-binding protein; Zfp-100; Zinc finger and BTB domain-containing protein 17; Zinc finger protein 100; Zinc finger protein 151; zinc finger protein 151 (pHZ-67); Zinc finger protein 60; Zinc finger protein Z13
基因别名: AA589413; Lp-1; MIZ-1; MIZ1; mZ13; pHZ-67; ZBTB17; Zfp100; ZNF151; ZNF60
UniProt ID: (Human) Q13105, (Mouse) Q60821
Entrez Gene ID: (Human) 7709, (Rat) 313666, (Mouse) 22642
gastrulation with mouth forming second
transcription, DNA-templated
ectoderm development
IRE1-mediated unfolded protein response
negative regulation of cell cycle
positive regulation of transcription, DNA-templated
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
regulation of transcription, DNA-templated
multicellular organism development
