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ZBTB20 Antibody (PA5-31896) in ICC/IF
ZBTB20 Polyclonal Antibody detects ZBTB20 protein by immunofluorescent analysis. Sample: DIV10 rat E18 primary hippocampal neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ZBTB20 stained by ZBTB20 Polyclonal Antibody (Product # PA5-31896) diluted at 1:500. Red: Tau, stained by Phospho-Tau (Ser262) Polyclonal Antibody [GT287]diluted at 1:500. Blue: Fluoroshield with DAPI .
产品信息
PA5-31896
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein fragment corresponding to a region within amino acids 1 and 668 of Human ZBTB20
偶联物
形式
Liquid
浓度
1.17 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2549369
产品详细信息
Recommended positive controls: 293T, NIH-3T3, JC, BCL-1.
Predicted reactivity: Mouse (100%), Rat (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BTB/POZ domain zinc finger factor HOF; BTB/POZ zinc finger protein DPZF; dendritic cell-derived BTB/POZ zinc finger; Dendritic-derived BTB/POZ zinc finger protein; POZ/zinc finger transcription factor ODA-8; Zinc finger and BTB domain-containing protein 20; Zinc finger protein 288
基因别名: 1300017A20Rik; 7330412A13Rik; A930017C21Rik; D16Wsu73e; DPZF; HOF; ODA-8S; Oda8; PRIMS; RGD1560387; ZBTB20; Zfp288; ZNF288
UniProt ID: (Human) Q9HC78, (Mouse) Q8K0L9
Entrez Gene ID: (Human) 26137, (Rat) 288105, (Mouse) 56490
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
positive regulation of interferon-beta production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
