Invitrogen

ZBTB6 Polyclonal Antibody

ZBTB6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 1

ZBTB6 Antibody (PA5-62922) in IHC (P)

Immunohistochemical analysis of ZBTB6 in human tonsil using ZBTB6 Polyclonal Antibody (Product # PA5-62922) shows strong nuclear positivity in a subset of non-germinal center cells. Germinal center cells exhibited moderate cytoplasmic and nuclear staining in a fraction of cells.

Product Image Gallery

产品信息

PA5-62922

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:200-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human ZBTB6. Recombinant protein control fragment (Product #RP-101569).

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2649782

产品详细信息

Immunogen sequence: CTEPLSKYLE IDLSMKNNNQ HTDLCQSSDP DVKNEDENSD KDCEIIEISE DSPVNIDFHV K

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 89%.

靶标信息

The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB6, also known as ZNF482, is highly expressed in brain. While little is known about ZBTB6, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB family member, ZBTB5, also acts as a transcriptional repressor, and can interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, suggesting that ZBTB6 may also act as a transcriptional repressor.

仅用于科研。不用于诊断过程。未经明确授权不得转售。