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产品信息
IHC-00730
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 250 and 300 of Human zinc finger, CCHC domain containing 11.
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Dog, Panda, Gorilla, Chimpanzee, Naked mole rat, Chinese hamster, Ferret and White-tufted-ear marmoset
靶标信息
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PAP associated domain containing 3; RP23-406B13.1; Terminal uridylyltransferase 4; TUTase 4; Zinc finger CCHC domain-containing protein 11; zinc finger, CCHC domain containing 11
基因别名: 6030404K05Rik; 9230115F04Rik; KIAA0191; mKIAA0191; PAPD3; PPAPD3; TUT4; ZCCHC11
UniProt ID: (Human) Q5TAX3, (Mouse) B2RX14
Entrez Gene ID: (Human) 23318, (Mouse) 230594
miRNA metabolic process
miRNA catabolic process
stem cell population maintenance
pre-miRNA processing
RNA 3'-end processing
histone mRNA catabolic process
cytokine production
gene silencing by RNA
regulation of lipopolysaccharide-mediated signaling pathway
negative regulation of NF-kappaB transcription factor activity
positive regulation of interleukin-6 production
interleukin-6-mediated signaling pathway
