Invitrogen

ZFAT Polyclonal Antibody

ZFAT Antibody in Immunocytochemistry (ICC/IF)

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ZFAT Antibody (PA5-32037) in ICC/IF

ZFAT Polyclonal Antibody detects ZFAT protein at nucleus by immunofluorescent analysis. Sample: SKNSH cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ZFAT protein stained by ZFAT Polyclonal Antibody (Product # PA5-32037) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.

ZFAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

PA5-32037

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 825 and 1083 of Human ZFAT

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.71 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 20% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2549510

产品详细信息

Recommended positive controls: Jurkat, Raji.

Predicted reactivity: Mouse (97%), Rat (97%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ZFAT zinc finger 1; zinc finger and AT hook domain containing; Zinc finger gene in AITD susceptibility region; zinc finger gene in autoimmune thyroid disease; zinc finger protein 403; Zinc finger protein 406; Zinc finger protein ZFAT; zinc-finger gene in AITD susceptibility region

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基因别名: AITD3; Gm922; KIAA1485; ZFAT; ZFAT1; Zfp406; ZNF406

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UniProt ID: (Human) Q9P243, (Mouse) Q7TS63

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Entrez Gene ID: (Human) 57623, (Mouse) 380993

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功能

RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding metal ion binding nucleic acid binding DNA binding C2H2 zinc finger transcription factor

参与通路

hematopoietic progenitor cell differentiation transcription from RNA polymerase II promoter multicellular organism development positive regulation of transcription from RNA polymerase II promoter spongiotrophoblast layer development transcription, DNA-templated regulation of transcription, DNA-templated hemopoiesis