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Product Details
PA5-119983
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within human ZFX aa 382-427
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913555
Product Specific Information
Positive Control: NCCIT
Subcellular Location: Cell nucleus
Target Information
ZFX is a member of the Kruppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: X-linked zinc finger protein; zinc finger protein X-linked 5; zinc finger protein X-linked 6; Zinc finger X-chromosomal protein
Gene Aliases: ZFX; Zfx5; Zfx5,6; Zfx6; ZNF926
UniProt ID: (Human) P17010, (Mouse) P17012
Entrez Gene ID: (Human) 7543, (Mouse) 22764
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
ovarian follicle development
germ cell development
spermatogenesis
fertilization
embryo development
post-embryonic development
obsolete death
multicellular organism growth
oocyte development
homeostasis of number of cells
parental behavior
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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