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产品信息
PA5-57696
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2649927
产品详细信息
Immunogen sequence: KHYKQQRGKQ KWFMKQNTEE STIGRKLSDH KLNNTPDSDW LQLKPLAGTD DSVVSEDRLN ETELTDLEGQ QESPPKNYLC IEEEKIIDHS HSDGL
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
靶标信息
ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: solute carrier family 39 (metal ion transporter), member 10; solute carrier family 39 (zinc transporter), member 10; Solute carrier family 39 member 10; Zinc transporter ZIP10; ZIP-10; Zrt- and Irt-like protein 10
基因别名: KIAA1265; LZT-Hs2; SLC39A10; ZIP10
UniProt ID: (Human) Q9ULF5
Entrez Gene ID: (Human) 57181
