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Immunogen sequence: SPSSKLSSVA SNGGGAGGAG GGAAGDKDTK SGPLKLSDIG VEDKSSFKPY SKPGSDKKEP GGGGGGGGGG GGGGGGVSSE KSGFRVPSAT CQPFTPRTGS PSSSASACSP GGMLSSAGGA PEGKDDKKDT DVG
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
The ZNF503 gene encodes zinc finger protein 503, a transcription factor involved in the regulation of developmental processes and cellular differentiation. ZNF503 contains zinc finger domains that enable it to bind DNA and modulate the transcription of specific target genes, influencing pathways critical for embryonic development, particularly in the neural and mesenchymal tissues. It plays a substantial role in the regulation of stem cell differentiation and has been implicated in various biological processes, including neuronal migration, immune response, and organogenesis. Alterations in ZNF503 expression have been linked to developmental anomalies and diseases such as cancers, where it affects tumor growth and progression by modulating gene networks involved in cell proliferation and differentiation. Research into ZNF503 focuses on understanding its complex regulatory functions and potential as a target for therapeutic interventions in developmental disorders and oncological applications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Zinc finger protein 503
Gene Aliases: Nlz2; NOLZ-1; NOLZ1; ZNF503
UniProt ID: (Human) Q96F45
Entrez Gene ID: (Human) 84858
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