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alpha COP Antibody (MA5-37942) in IHC (P)
Immunohistochemistry analysis of alpha COP in paraffin-embedded human colon carcinoma. Samples were incubated with alpha COP Monoclonal antibody (Product # MA5-37942) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
产品信息
MA5-37942
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC2215
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human COPA (P53621)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2897862
产品详细信息
Positive Samples: HeLa, HT-29, MCF7, Mouse lung, Rat brain
Immunogen sequence: MLTKFETKSA RVKGLSFHPK RPWILTSLHN GVIQLWDYRM CTLIDKFDEH DGPVRGIDFH KQQPLFVSGG DDYKIKVWNY KLRRCLFTLL GHLDYIRTTF
靶标信息
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha coat protein; Alpha-coat protein; Alpha-COP; Coatomer subunit alpha; HEP-COP; HEPCOP; proxenin; xenin
基因别名: AILJK; AU040324; COPA; HEP-COP; xenin
UniProt ID: (Human) P53621, (Mouse) Q8CIE6
Entrez Gene ID: (Human) 1314, (Mouse) 12847, (Rat) 304978
