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beta-3 Adrenergic Receptor Antibody (PA5-50914) in WB
Western blot was performed using Anti-beta-3 Adrenergic Receptor Polyclonal Antibody (Product # PA5-50914) and a 75 kDa band corresponding to beta-3 Adrenergic Receptor was observed in 3T3-L1 differentiated to adipocytes and Mouse Brown Adipose tissue with little or no expression in 3T3-L1, Mouse Adipose tissue, Mouse Liver, Rat Liver and Mouse Brain which are reported negative for beta-3 Adrenergic Recepto... View More
产品信息
PA5-50914
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from the Internal region of human AR-beta 3 (aa 250-299).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 0.5% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2636362
产品详细信息
ADRB3 Polyclonal Antibody detects endogenous levels of ADRB3 protein.
靶标信息
beta 3 Adrenergic Receptor is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Beta adrenergic receptors are involved in the epinephrine and norepinephrine-induced activation of adenylate cyclase through the action of G proteins. beta 3 Adrenergic Receptor expression has been documented in adipose tissues, heart, and in smooth muscle of digestive and urinary tract organs (bladder, colon, small intestine, stomach, ureter). Utilization of alternate promoters and/or 3-prime untranslated regions may result in tissue-specific regulation of the expression of this protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: adrenergic receptor, beta 3; adrenergic, beta-3-, receptor; beta 3 adrenoceptor; beta 3-AR; Beta-3 adrenergic receptor; Beta-3 adrenoceptor; Beta-3 adrenoreceptor; Beta-3 AR; beta3-adrenergic receptor; beta3-Adrenoreceptor; Beta3-AR; FLJ99960
基因别名: ADRB; Adrb-3; ADRB3; ADRB3R; B3AR; B3bar; BETA3AR
UniProt ID: (Human) P13945, (Mouse) P25962, (Rat) P26255
Entrez Gene ID: (Human) 155, (Mouse) 11556, (Rat) 25645
beta-adrenergic receptor activity
protein binding
beta3-adrenergic receptor activity
beta-3 adrenergic receptor binding
protein homodimerization activity
epinephrine binding
norepinephrine binding
signal transducer activity
G-protein coupled receptor activity
adrenergic receptor activity
G-protein coupled receptor
temperature homeostasis
diet induced thermogenesis
vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
desensitization of G-protein coupled receptor protein signaling pathway by arrestin
carbohydrate metabolic process
generation of precursor metabolites and energy
energy reserve metabolic process
receptor-mediated endocytosis
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
cell-cell signaling
aging
response to cold
heat generation
negative regulation of multicellular organism growth
eating behavior
positive regulation of MAPK cascade
response to antibiotic
brown fat cell differentiation
adenylate cyclase-activating adrenergic receptor signaling pathway
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adrenergic receptor signaling pathway
