Invitrogen

beta-Defensin 1 Polyclonal Antibody

beta-Defensin 1 Antibody in Western Blot (WB)

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beta-Defensin 1 Antibody (PA5-75666) in WB

Western blot analysis of beta-Defensin 1 in Lane 1: HEK293T whole cell lysate, Lane 2: mouse liver tissue lysate, Lane 3: rat heart tissue lysate. Samples were incubated with beta-Defensin 1 polyclonal antibody (Product # PA5-75666) at a dilution of 1:500.

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产品信息

PA5-75666

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看2篇已发表文章 2篇已发表文章

免疫组化（石蜡） (IHC (P))

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to residues in Human beta-Defensin 1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2719394

产品详细信息

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

靶标信息

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

N-(3',4'-dimethoxycinnamonyl) anthranilic acid alleviates severe acute pancreatitis by inhibiting intestinal barrier dysfunction and NF-κB activation.

Drug development research

Zhao Z,Lu L,Li W

PA5-75666 was used in Western Blotting to investigate the role of anthranilic acid active synthetic derivative, N-(3',4'-dimethoxycinnamonyl) anthranilic acid (3,4-DAA), in intestinal barrier dysfunction of SAP.

Sat May 01 00:00:00 UTC 2021

N-(3',4'-dimethoxycinnamonyl) anthranilic acid alleviates severe acute pancreatitis by inhibiting intestinal barrier dysfunction and NF-κB activation.

Drug development research

Zhao Z,Lu L,Li W

Sat May 01 00:00:00 UTC 2021

Disruption of autophagy by increased 5-HT alters gut microbiota and enhances susceptibility to experimental colitis and Crohn's disease.

Science advances

Haq S,Wang H,Grondin J,Banskota S,Marshall JK,Khan II,Chauhan U,Cote F,Kwon YH,Philpott D,Brumell JH,Surette M,Steinberg GR,Khan WI

PA5-75666 was used in Western Blot to study the impact of the interaction between serotonin (5-hydroxytryptamine) and autophagy in colitis in mouse and human studies.

Fri Nov 05 00:00:00 UTC 2021

Disruption of autophagy by increased 5-HT alters gut microbiota and enhances susceptibility to experimental colitis and Crohn's disease.

Science advances

Haq S,Wang H,Grondin J,Banskota S,Marshall JK,Khan II,Chauhan U,Cote F,Kwon YH,Philpott D,Brumell JH,Surette M,Steinberg GR,Khan WI

PA5-75666 was used in Western Blot to study the impact of the interaction between serotonin (5-hydroxytryptamine) and autophagy in colitis in mouse and human studies.