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delta Catenin Antibody (PA5-32528) in IHC (P)
Immunohistochemical (paraffin) analysis of Catenin delta 1 (p120) using anti-Catenin delta 1 (p120) Polyclonal Antibody (Product # PA5-32528) in Breast Lobular Carcinoma Cancer Tissue. The recommended dilution for this antibody in immunohistochemistry applications is 1:100.
产品信息
PA5-32528
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to C-terminus of human p120.
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.6, with 1% BSA
内含物
0.1% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2549994
产品详细信息
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is breast lobular carcinoma.
靶标信息
Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin-associated protein), delta 1; Catenin delta-1; catenin src; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(cas); p120(ctn); p120-catenin
基因别名: AA409437; AU019353; CAS; Catns; CTNND; CTNND1; KIAA0384; mKIAA0384; P120; p120(CAS); p120(CTN); P120CAS; P120CTN
UniProt ID: (Human) O60716, (Mouse) P30999
Entrez Gene ID: (Human) 1500, (Mouse) 12388
transcription, DNA-templated
regulation of transcription, DNA-templated
cell adhesion
brain development
Wnt signaling pathway
single organismal cell-cell adhesion
adherens junction organization
negative regulation of canonical Wnt signaling pathway
morphogenesis of a polarized epithelium
salivary gland morphogenesis
keratinocyte differentiation
epithelial cell differentiation involved in salivary gland development
