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This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: eIF-2B GDP-GTP exchange factor subunit alpha; eIF2B GDP-GTP exchange factor subunit alpha; eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Translation initiation factor eIF2B subunit alpha
基因别名: EIF2B; EIF2B1; EIF2BA
UniProt ID: (Human) Q14232
Entrez Gene ID: (Human) 1967