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eIF2b gamma Antibody (PA5-106759) in ICC/IF
Immunocytochemistry analysis of eIF2b gamma in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with eIF2b gamma polyclonal antibody (Product # PA5-106759) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugat... View More
产品信息
PA5-106759
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human EIF2B3(Accession Q9NR50), corresponding to amino acid residues F266-L316.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854427
产品详细信息
Antibody detects endogenous levels of total EIF2B3.
靶标信息
EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: eIF-2B GDP-GTP exchange factor subunit gamma; eIF2B GDP-GTP exchange factor subunit gamma; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; translation initiation factor eIF-2B subunit gamma; Translation initiation factor eIF2B subunit gamma
基因别名: 1190002P15Rik; EIF-2B; EIF2B3; EIF2Bgamma
UniProt ID: (Human) Q9NR50
Entrez Gene ID: (Human) 8891, (Mouse) 108067
