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eIF2b gamma Antibody (MA1-078) in ICC/IF
Immunofluorescent analysis of eIF2B3 (green) showing staining in the cytoplasm of COS7 cells (right) compared to a negative control without primary antibody (left). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with an eIF2B3 monoclonal antibody (Product # MA1-078) in 3% BSA-PBS at a di... View More
产品信息
MA1-078
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Non-human primate,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1H3
抗原
Full length human eIF2B3 produced in HEK293T cells.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 1mg/mL BSA, 30% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2536735
产品详细信息
MA1-078 detects eIF2B3 in human, non-human primate and rat samples and has been successfully used in Western blot, ICC/IF, IHC (P) and immunoprecipitation applications.
The immunogen for MA1-078 is full length human eIF2B3 produced in HEK293T cells.
靶标信息
EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: eIF-2B GDP-GTP exchange factor subunit gamma; eIF2B GDP-GTP exchange factor subunit gamma; eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD); eukaryotic translation initiation factor 2B, subunit 3 gamma; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; translation initiation factor eIF-2B subunit gamma; Translation initiation factor eIF2B subunit gamma
基因别名: EIF-2B; EIF2B3; Eif2bg; EIF2Bgamma
UniProt ID: (Human) Q9NR50, (Rat) P70541
Entrez Gene ID: (Human) 8891, (Rat) 171145
