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eIF4G3 Antibody (PA5-55214) in IHC
Immunohistochemical staining of eIF4G3 in human cerebral cortex, lymph node, skeletal muscle and testis using eIF4G3 Polyclonal Antibody (Product # PA5-55214) (A) shows similar protein distribution across tissues to an independent eIF4G3 Polyclonal Antibody (B).
产品信息
PA5-55214
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640976
产品详细信息
Immunogen sequence: VARSTIAAPT SSALSSQPIF TTAIDDRCEL SSPREDTIPI PSLTSCTETS DPLPTNENDD DICKKPCSVA PNDIPLV
Highest antigen sequence identity to the following orthologs: Mouse - 56%, Rat - 49%.
靶标信息
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: eIF-4-gamma 3; eIF-4-gamma II; eIF4GII; Eukaryotic translation initiation factor 4 gamma 3; RP11-190H11.1
基因别名: eIF-4G 3; eIF4G 3; EIF4G3; eIF4GII
UniProt ID: (Human) O43432
Entrez Gene ID: (Human) 8672
