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产品信息
PA5-69808
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of mouse gamma Adaptin
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2691168
产品详细信息
This target displays homology in the following species: Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%
靶标信息
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
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生物信息学
蛋白别名: adapter-related protein complex 1 subunit gamma-1; Adaptor protein complex AP-1 subunit gamma-1; Adaptor-related protein complex 1 subunit gamma-1; AP-1 complex subunit gamma-1; Clathrin assembly protein complex 1 gamma-1 large chain; Gamma-adaptin; Gamma1-adaptin; Golgi adaptor HA1/AP1 adaptin subunit gamma-1; MGC18255
基因别名: AA409002; Adtg; Ap1g1; AU041323; AW551707; Clapg1; D8Ertd374e
UniProt ID: (Mouse) P22892
Entrez Gene ID: (Mouse) 11765
microtubule cytoskeleton organization
transport
intracellular protein transport
protein transport
vesicle-mediated transport
endosome to melanosome transport
positive regulation of natural killer cell degranulation
positive regulation of natural killer cell mediated cytotoxicity
Golgi to lysosome transport
