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gamma Catenin Antibody (PA5-18064) in IHC (P)
Immunohistochemistry analysis of gamma Catenin in human heart. Samples were incubated with gamma Catenin polyclonal antibody (Product # PA5-18064) using a dilution of 5 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
产品信息
PA5-18064
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (GLRPPYPTADHMLA) corresponding to the C-terminus amino acids of JUP (aa 732-745).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10985728
产品详细信息
This antibody is predicted to react with canine, mouse and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; gamma-catenin; gamma-catenin (plakoglobin); Junction plakoglobin; OTTHUMP00000164735
基因别名: ARVD12; CTNNG; D930025P04Rik; DP3; DPIII; JUP; PDGB; PG; PKGB
UniProt ID: (Human) P14923, (Rat) Q6P0K8, (Mouse) Q02257
Entrez Gene ID: (Human) 3728, (Rat) 81679, (Mouse) 16480
transcription coactivator activity
signal transducer activity
structural molecule activity
structural constituent of cell wall
protein binding
protein kinase binding
protein phosphatase binding
protein homodimerization activity
alpha-catenin binding
cadherin binding
cell adhesion molecule binding
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
cadherin binding involved in cell-cell adhesion
nuclear hormone receptor binding
desmosome assembly
cytoskeletal anchoring at plasma membrane
signal transduction
single organismal cell-cell adhesion
cell migration
adherens junction organization
adherens junction assembly
regulation of cell proliferation
positive regulation of protein import into nucleus
skin development
detection of mechanical stimulus
positive regulation of sequence-specific DNA binding transcription factor activity
protein heterooligomerization
endothelial cell-cell adhesion
cellular response to indole-3-methanol
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
establishment of protein localization to plasma membrane
positive regulation of canonical Wnt signaling pathway
regulation of ventricular cardiac muscle cell action potential
cell adhesion
regulation of cell fate specification
positive regulation of transcription from RNA polymerase II promoter
ventricular cardiac muscle cell action potential
bundle of His cell to Purkinje myocyte communication
regulation of nucleic acid-templated transcription
