Invitrogen

gamma Catenin Recombinant Rabbit Monoclonal Antibody (JF0973)

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查看其他33个gamma Catenin抗体
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说明书
实验方案
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产品信息

MA5-32515

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:2,000
-

免疫组化（石蜡） (IHC (P))

1:50-1:200
-

免疫细胞化学 (ICC/IF)

1:100-1:500
-

流式细胞分析 (Flow)

1:50-1:100
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

JF0973

抗原

Recombinant protein within Human gamma Catenin aa 10-116
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2809792

产品详细信息

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; gamma-catenin; gamma-catenin (plakoglobin); Junction plakoglobin; OTTHUMP00000164735

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基因别名: ARVD12; CTNNG; D930025P04Rik; DP3; DPIII; JUP; PDGB; PG; PKGB

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UniProt ID: (Human) P14923, (Rat) Q6P0K8, (Mouse) Q02257

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Entrez Gene ID: (Human) 3728, (Rat) 81679, (Mouse) 16480

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功能
transcription coactivator activity signal transducer activity structural molecule activity structural constituent of cell wall protein binding protein kinase binding protein phosphatase binding protein homodimerization activity alpha-catenin binding cadherin binding cell adhesion molecule binding cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication cadherin binding involved in cell-cell adhesion nuclear hormone receptor binding
参与通路
desmosome assembly cytoskeletal anchoring at plasma membrane signal transduction single organismal cell-cell adhesion cell migration adherens junction organization adherens junction assembly regulation of cell proliferation positive regulation of protein import into nucleus skin development detection of mechanical stimulus positive regulation of sequence-specific DNA binding transcription factor activity protein heterooligomerization endothelial cell-cell adhesion cellular response to indole-3-methanol bundle of His cell-Purkinje myocyte adhesion involved in cell communication regulation of heart rate by cardiac conduction establishment of protein localization to plasma membrane positive regulation of canonical Wnt signaling pathway regulation of ventricular cardiac muscle cell action potential cell adhesion regulation of cell fate specification positive regulation of transcription from RNA polymerase II promoter ventricular cardiac muscle cell action potential bundle of His cell to Purkinje myocyte communication regulation of nucleic acid-templated transcription
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