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产品信息
PA5-43844
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human BMPER (aa 501-550).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2606629
产品详细信息
Peptide sequence: NGHKRDDLIG GDGNFKFDVD DFAESWRVES NEFCNRPQRK PVPELCQGTV
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 79%
靶标信息
BMPER contains 1 TIL (trypsin inhibitory-like) domain, 5 VWFC domains and 1 VWFD domain.BMPER is the inhibitor of bone morphogenetic protein (BMP) functions. It may regulate BMP responsiveness of osteoblasts and chondrocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMP-binding endothelial regulator precursor protein; BMP-binding endothelial regulator protein; Bone morphogenetic protein-binding endothelial cell precursor-derived regulator; crossveinless 2; crossveinless-2; hCV2; Protein crossveinless-2
基因别名: BMPER; CRIM3; CV-2; CV2; KIAA1965
UniProt ID: (Human) Q8N8U9
Entrez Gene ID: (Human) 168667
ureteric bud development
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
regulation of endothelial cell migration
negative regulation of BMP signaling pathway
endothelial cell activation
endothelial cell differentiation
inner ear development
regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of ERK1 and ERK2 cascade
