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hnRNP C1/C2 Antibody (PA5-75278) in IHC (P)
Immunohistochemistry analysis of hnRNP C1/C2 in paraffin-embedded human colon carcinoma tissue. Samples were incubated with hnRNP C1/C2 polyclonal antibody (Product # PA5-75278) using a dilution of 1:50 (showing nucleus staining). Secondary antibody: Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase. Negative control (the right) using PBS instead of primary antibody.
产品信息
PA5-75278
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 241-290 of Human hnRNP C1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719006
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: heterogeneous nuclear ribonucleoprotein C; heterogeneous nuclear ribonucleoprotein C (C1/C2); Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C protein C-terminal fragment (158 AA); hnRNP C1/C2; hnRNP core protein C; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein
基因别名: C1; C2; HNRNP; hnRNP C; HNRNPC; HNRPC; SNRPC
UniProt ID: (Human) P07910
Entrez Gene ID: (Human) 3183, (Rat) 290046
nucleotide binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA binding
mRNA 3'-UTR binding
protein binding
poly(U) RNA binding
nucleosomal DNA binding
identical protein binding
poly(A) RNA binding
telomerase RNA binding
N6-methyladenosine-containing RNA binding
nucleic acid binding
mRNA binding
