Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 14
hnRNP C1/C2 Antibody (MA5-32270) in ICC/IF
Immunofluorescence analysis of HNRNPC was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with hnRNP C1/C2 Recombinant Rabbit Monoclonal Antibody (SN0652) (Product # MA5-32270) at 1:100 dilution in 0.1% BSA, inc... View More
产品信息
MA5-32270
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat,
Zebrafish
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
SN0652
抗原
Recombinant protein of Human HNRNPC aa 60-190
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2809556
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: heterogeneous nuclear ribonucleoprotein C; heterogeneous nuclear ribonucleoprotein C (C1/C2); heterogeneous nuclear ribonucleoprotein C1; heterogeneous nuclear ribonucleoprotein C2; Heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous ribonucleoprotein C1/C2; hnRNP C protein C-terminal fragment (158 AA); hnRNP C1 / hnRNP C2; hnRNP C1/C2; hnRNP C2; hnRNP core protein C; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; snoRNA MBI-122
基因别名: AL022939; bZ1G18.4; C1; C2; D14Wsu171e; fb57h12; fi16b11; HNRNP; hnRNP C; hnrnp-C; HNRNPC; hnRNPC1; hnRNPC2; HNRPC; Hnrpc1; Hnrpc2; SNRPC; wu:fb57h12; wu:fi16b11; zgc:55701
UniProt ID: (Human) P07910, (Mouse) Q9Z204
Entrez Gene ID: (Human) 3183, (Rat) 290046, (Mouse) 15381, (Zebrafish) 406352
nucleotide binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA binding
mRNA 3'-UTR binding
protein binding
poly(U) RNA binding
nucleosomal DNA binding
identical protein binding
poly(A) RNA binding
telomerase RNA binding
N6-methyladenosine-containing RNA binding
nucleic acid binding
mRNA binding
