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hnRNP DL Antibody (PA5-103885) in ICC/IF
Immunofluorescent analysis of hnRNP DL in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and hnRNP DL polyclonal antibody (Product # PA5-103885) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-103885
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human HNRNPDL(Accession O14979), corresponding to amino acid residues G385-Y420.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853217
产品详细信息
Antibody detects endogenous levels of total HNRPDL.
靶标信息
hnRNP DL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A+U-rich element RNA binding factor; AU-rich element RNA-binding factor; Heterogeneous nuclear ribonucleoprotein D-like; hnRNP D-like; hnRNP DL; hnRNP-DL; hnRPD-like protein; JKT41-binding protein; Protein laAUF1
基因别名: AA407431; AA959857; D5Ertd650e; D5Wsu145e; HNRNP; hnRNP DL; hnRNP-DL; HNRNPDL; Hnrnpdl1; HNRPDL; JKTBP; JKTBP2; laAUF1; LGMD1G
UniProt ID: (Human) Q96S43, (Rat) Q3SWU3
Entrez Gene ID: (Human) 9987, (Rat) 305178, (Mouse) 50926
