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产品信息
PA1-30151
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Rat mGlurR2/3 residues 860-872 (NGREVVDSTTSSL)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_1958342
产品详细信息
PA1-30151 detects mGluR2 + mGluR3 from rat samples.
Sequence is 100% conserved between mGluR2 and mGluR3. Predicted to react with human and mouse.
靶标信息
The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: glutamate receptor; M mGlu3; Metabotropic glutamate receptor 2; Metabotropic glutamate receptor 3; mGluR2; mGluR3
基因别名: Gprc1b; Gprc1c; Grm2; Grm3; Mglur2; Mglur3
UniProt ID: (Rat) P31421, (Rat) P31422
Entrez Gene ID: (Rat) 24415, (Rat) 24416
