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Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Marmoset (100%); Rat, Dog, Panda, Rabbit (83%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR17, NMDA13, KAI2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: glutamate receptor; glutamate receptor, metabotropic 6; Metabotropic glutamate receptor 6; mGluR6
基因别名: CSNB1B; GPRC1F; GRM6; mGlu6; MGLUR6
UniProt ID: (Human) O15303
Entrez Gene ID: (Human) 2916