Product References
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region.
Cell reports
Levy S,Somasundaram L,Raj IX,Ic-Mex D,Phal A,Schmidt S,Ng WI,Mar D,Decarreau J,Moss N,Alghadeer A,Honkanen H,Sarthy J,Vitanza A,Hawkins RD,Mathieu J,Wang Y,Baker D,Bomsztyk K,Ruohola-Baker H
MA5-14260 was used in Immunocytochemistry to identify a PRC2-controlled, functional TATA box >500 bp upstream of the TBX18 transcription start site (TSS) using EBdCas9.
Tue Mar 01 00:00:00 UTC 2022
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region.
Cell reports
Levy S,Somasundaram L,Raj IX,Ic-Mex D,Phal A,Schmidt S,Ng WI,Mar D,Decarreau J,Moss N,Alghadeer A,Honkanen H,Sarthy J,Vitanza A,Hawkins RD,Mathieu J,Wang Y,Baker D,Bomsztyk K,Ruohola-Baker H
MA5-14260 was used in Immunocytochemistry to identify a PRC2-controlled, functional TATA box >500 bp upstream of the TBX18 transcription start site (TSS) using EBdCas9.
Tue Mar 01 00:00:00 UTC 2022
NPM1 Mutational Status Underlines Different Biological Features in Pediatric AML.
Cancers
Tregnago C,Benetton M,Padrin D,Polato K,Borella G,Da Ros A,Marchetti A,Porcù E,Del Bufalo F,Mecucci C,Locatelli F,Pigazzi M
MA5-14260 was used in Western Blotting to identify that the NPM1 mutational status mediates crucial biological characteristics of AML cells, providing the basis for further sub-classification and, potentially, management of this subgroup of patients.
Sat Jul 10 00:00:00 UTC 2021
NPM1 Mutational Status Underlines Different Biological Features in Pediatric AML.
Cancers
Tregnago C,Benetton M,Padrin D,Polato K,Borella G,Da Ros A,Marchetti A,Porcù E,Del Bufalo F,Mecucci C,Locatelli F,Pigazzi M
MA5-14260 was used in Western Blotting to identify that the NPM1 mutational status mediates crucial biological characteristics of AML cells, providing the basis for further sub-classification and, potentially, management of this subgroup of patients.
Sat Jul 10 00:00:00 UTC 2021
Nuclear MET requires ARF and is inhibited by carbon nanodots through binding to phospho-tyrosine in prostate cancer.
Oncogene
Xie Y,Fan H,Lu W,Yang Q,Nurkesh A,Yeleussizov T,Maipas A,Lu J,Manarbek L,Chen Z,Benassi E
MA5-14260 was used in Immunocytochemistry to reveal for the first time that targeting nMET axis by carbon nanodots can be a novel avenue for overcoming drug resistance in cancers especially prostate cancer.
Mon Apr 01 00:00:00 UTC 2019
Nuclear MET requires ARF and is inhibited by carbon nanodots through binding to phospho-tyrosine in prostate cancer.
Oncogene
Xie Y,Fan H,Lu W,Yang Q,Nurkesh A,Yeleussizov T,Maipas A,Lu J,Manarbek L,Chen Z,Benassi E
MA5-14260 was used in Immunocytochemistry to reveal for the first time that targeting nMET axis by carbon nanodots can be a novel avenue for overcoming drug resistance in cancers especially prostate cancer.
Mon Apr 01 00:00:00 UTC 2019
MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo.
Oncotarget
Xie Y,Lu W,Liu S,Yang Q,Goodwin JS,Sathyanarayana SA,Pratap S,Chen Z
MA514260 was used in immunocytochemistry and western blot to explore the interaction between ARF and MMP7 in prostate cancer
Tue Jul 26 00:00:00 UTC 2016
A patient with a noninvasive mucinous ovarian borderline tumor presenting with late pleural metastases.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
Simons M,Nagtegaal ID,Overbeek LI,Flucke U,Massuger LF,Bulten J
MA5-14260 was used in immunohistochemistry - paraffin section to describe a patient diagnosed with a noninvasive intestinal-type mucinous ovarian borderline tumor presenting with pleural metastases
Sun Mar 01 00:00:00 UTC 2015
MDM2-mediated degradation of p14ARF: a novel mechanism to control ARF levels in cancer cells.
PloS one
Vivo M,Matarese M,Sepe M,Di Martino R,Festa L,Calabrò V,La Mantia G,Pollice A
MA5-14260 was used in Immunocytochemistry to elucidate a novel relationship between the human p14ARF oncosuppressor and the MDM2 oncoprotein.
Mon Nov 23 00:00:00 UTC 2015
MDM2-mediated degradation of p14ARF: a novel mechanism to control ARF levels in cancer cells.
PloS one
Vivo M,Matarese M,Sepe M,Di Martino R,Festa L,Calabrò V,La Mantia G,Pollice A
MA5-14260 was used in Immunocytochemistry to elucidate a novel relationship between the human p14ARF oncosuppressor and the MDM2 oncoprotein.
Mon Nov 23 00:00:00 UTC 2015
ARF represses androgen receptor transactivation in prostate cancer.
Molecular endocrinology (Baltimore, Md.)
Lu W,Xie Y,Ma Y,Matusik RJ,Chen Z
MA5-14260 was used in immunohistochemistry, immunoprecipitation, and western blot to study the role of p14ARP as an androgen receptor-interacting protein that blocks its transactivation in prostate cancer cells
Mon Apr 01 00:00:00 UTC 2013
Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation.
PloS one
Vivo M,Ranieri M,Sansone F,Santoriello C,Calogero RA,Calabrò V,Pollice A,La Mantia G
MA5-14260 was used in immunoprecipitation and western blot to report that p14ARF is a PKC target
Tue Jul 02 00:00:00 UTC 2013
p16INK4A-silencing augments DNA damage-induced apoptosis in cervical cancer cells.
Oncogene
Lau WM,Ho TH,Hui KM
MA5-14260 was used in western blot to study the role of p16INK4A-silencing in DNA damage-induced apoptosis in cervical cancer cells
Thu Sep 06 00:00:00 UTC 2007
Antiviral action of the tumor suppressor ARF.
The EMBO journal
García MA,Collado M,Muñoz-Fontela C,Matheu A,Marcos-Villar L,Arroyo J,Esteban M,Serrano M,Rivas C
MA5-14260 was used in western blot to study the role of the tumor suppressor ARF in viral infection surveillance
Wed Sep 20 00:00:00 UTC 2006
Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.
Oncogene
Hemmati PG,Güner D,Gillissen B,Wendt J,von Haefen C,Chinnadurai G,Dörken B,Daniel PT
MA5-14260 was used in western blot to study the ability of Bak to functionally complement for loss of Bax during mitochondrial apoptosis in human cancer cells
Thu Oct 26 00:00:00 UTC 2006
p14ARF, a prognostic predictor in HPV-negative vulvar carcinoma.
American journal of clinical pathology
Knopp S,Nesland JM,Tropé C,Holm R
MA5-14260 was used in immunohistochemistry to study the prognostic value of p14ARF in HPV-negative vulvar carcinoma
Tue Aug 01 00:00:00 UTC 2006
Vulvar squamous cell carcinoma is a multifactorial disease following two separate and independent pathways.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
van der Avoort IA,Shirango H,Hoevenaars BM,Grefte JM,de Hullu JA,de Wilde PC,Bulten J,Melchers WJ,Massuger LF
MA5-14260 was used in immunohistochemistry to study the pathways leading to vulvar squamous cell carcinoma
Sun Jan 01 00:00:00 UTC 2006
Ebp1 is a dsRNA-binding protein associated with ribosomes that modulates eIF2alpha phosphorylation.
Biochemical and biophysical research communications
Squatrito M,Mancino M,Sala L,Draetta GF
MA5-14260 was used in immunocytochemistry to characterize the localization of Ebp1 and its function
Fri Jun 09 00:00:00 UTC 2006
Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo.
PLoS genetics
Morris EJ,Michaud WA,Ji JY,Moon NS,Rocco JW,Dyson NJ
MA5-14260 was used in western blot to investigate the effect of Api5 on the E2F-dependent apoptosis in vivo
Fri Nov 17 00:00:00 UTC 2006
DNA damage disrupts the p14ARF-B23(nucleophosmin) interaction and triggers a transient subnuclear redistribution of p14ARF.
Cancer research
Lee C,Smith BA,Bandyopadhyay K,Gjerset RA
MA5-14260 was used in immunocytochemistry to investigate the impact of DNA damage on subnuclear distribution of ARF and its interaction with B23 in human tumor cells
Tue Nov 01 00:00:00 UTC 2005
Retracted: p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity.
The Journal of biological chemistry
Normand G,Hemmati PG,Verdoodt B,von Haefen C,Wendt J,Güner D,May E,Dörken B,Daniel PT
MA5-14260 was used in western blot to study the mechanism by which p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells
Fri Feb 25 00:00:00 UTC 2005
EBP1 is a nucleolar growth-regulating protein that is part of pre-ribosomal ribonucleoprotein complexes.
Oncogene
Squatrito M,Mancino M,Donzelli M,Areces LB,Draetta GF
MA5-14260 was used in immunocytochemistry to investigate the cellular function of EBP1
Thu May 27 00:00:00 UTC 2004
p14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2.
Breast cancer research : BCR
Vestey SB,Sen C,Calder CJ,Perks CM,Pignatelli M,Winters ZE
MA5-14260 was used in immunohistochemistry to study the expression and cellular distribution of p14ARF, p53 and Hdm2 in invasive breast cancers with ductal carcinoma in situ
Tue Oct 05 00:00:00 UTC 2004
Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathway.
Molecular and cellular biology
Shamanin VA,Androphy EJ
MA5-14260 was used in western blot to study the role of p14ARF-p53 pathway inactivation in the immortalization of human mammary epithelial cells
Mon Mar 01 00:00:00 UTC 2004
Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc.
The Journal of biological chemistry
Datta A,Nag A,Pan W,Hay N,Gartel AL,Colamonici O,Mori Y,Raychaudhuri P
MA5-14260 was used in immunoprecipitation to investigate the interaction of ARF with c-Myc and its influence on c-Myc function
Fri Aug 27 00:00:00 UTC 2004
Different requirements for the cytostatic and apoptotic effects of type I interferons. Induction of apoptosis requires ARF but not p53 in osteosarcoma cell lines.
The Journal of biological chemistry
Sandoval R,Xue J,Pilkinton M,Salvi D,Kiyokawa H,Colamonici OR
MA5-14260 was used in western blot to investigate the mechanism for the effect of type I interferons on cell death
Fri Jul 30 00:00:00 UTC 2004
Nitric oxide induces phosphorylation of p53 and impairs nuclear export.
Oncogene
Schneiderhan N,Budde A,Zhang Y,Brüne B
MA5-14260 was used in immunocytochemistry to study the role of nitric oxide in inducing the phosphorylation and impaired nuclear export of p53
Thu May 15 00:00:00 UTC 2003
A melanoma-predisposing germline CDKN2A mutation with functional significance for both p16 and p14ARF.
Cancer letters
Hashemi J,Lindström MS,Asker C,Platz A,Hansson J,Wiman KG
MA5-14260 was used in immunocytochemistry to investigate the effect of melanoma-predisposing germline CDKN2A mutation on p16 and p14ARF activation
Fri Jun 28 00:00:00 UTC 2002
p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.
Cancer research
Esteller M,Cordon-Cardo C,Corn PG,Meltzer SJ,Pohar KS,Watkins DN,Capella G,Peinado MA,Matias-Guiu X,Prat J,Baylin SB,Herman JG
MA5-14260 was used in western blot to study the effects of epigenetic silencing of p14ARF on the subcellular localization of MDM2
Sun Apr 01 00:00:00 UTC 2001
Aberrant expression of tumor suppressor proteins in the Ewing family of tumors.
Archives of pathology & laboratory medicine
Maitra A,Roberts H,Weinberg AG,Geradts J
MA5-14260 was used in immunohistochemistry to investigate tumor suppressor proteins in the Ewing family of tumors
Sat Sep 01 00:00:00 UTC 2001
