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p53DINP1 Antibody (PA5-96989) in WB
Western blot analysis of p53DINP1 in extracts of various cell lines. Samples were incubated with p53DINP1 Polyclonal antibody (Product # PA5-96989) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
产品信息
PA5-96989
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p53 DINP1 (NP_0011292051)
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808791
产品详细信息
Immunogen sequence: MFQRLNKMFV GEVSSSSNQE PEFNEKEDDE WILVDFIDTC TGFSAEEEEE EEDISEESPT EHPSVFSCLP ASLECLADTS DSCFLQFESC PMEESWFITP; Positive Samples: Mouse spleen, Mouse lung; Cellular Location: Cytoplasm, Cytoplasmic vesicle, Nucleus, PML body, autophagosome, cytosol
靶标信息
A novel p53 inducible gene was identified and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein). p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: p53-dependent damage-inducible nuclear protein 1; p53DINP1; stress induced protein; Stress-induced protein; TEAP; thymus expressed acidic protein; Thymus-expressed acidic protein; Tumor protein p53-inducible nuclear protein 1
基因别名: 2700057G22Rik; SIP; SIP18; SIP27; Stinp; Teap; Trp53inp1
UniProt ID: (Mouse) Q9QXE4
Entrez Gene ID: (Mouse) 60599
autophagosome assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
autophagy
apoptotic process
cell cycle arrest
negative regulation of cell proliferation
response to heat
regulation of autophagy
positive regulation of autophagy
negative regulation of cell migration
cellular response to UV
positive regulation of apoptotic process
positive regulation of transcription, DNA-templated
autophagic cell death
cellular response to ethanol
cellular response to hydroperoxide
cellular response to methyl methanesulfonate
positive regulation of apoptotic signaling pathway
