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产品信息
MA5-42878
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
9Y6Z7
抗原
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human p53 DINP1 (Q96A56).
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2912019
产品详细信息
Positive test controls include: HepG2, A-549, BxPC-3, RAW264.7, C6, Mouse lung, Mouse liver, Rat lung.
Immunogen sequence: PPPCFTAGGL TTIKVETSPM ENLLIEHPSM SVYAVHNSCP GLSEATRGTD ELHSPSSPRV EAQNEMGQHI HCYVAALAAH TTFLEQPKSF RPSQWIKEHS E
靶标信息
A novel p53 inducible gene was identified and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein). p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: p53-dependent damage-inducible nuclear protein 1; p53-inducible p53DINP1; p53DINP1; stress induced protein; Stress-induced protein; TEAP; thymus expressed acidic protein; Thymus-expressed acidic protein; transformation related protein 53 inducible nuclear protein 1; Tumor protein p53-inducible nuclear protein 1
基因别名: 2700057G22Rik; P53DINP1; SIP; SIP18; SIP27; Stinp; Teap; TP53DINP1; TP53INP1; TP53INP1A; TP53INP1B; Trp53inp1
UniProt ID: (Human) Q96A56, (Rat) Q80YE2, (Mouse) Q9QXE4
Entrez Gene ID: (Human) 94241, (Rat) 297822, (Mouse) 60599
autophagosome assembly
transcription, DNA-templated
apoptotic process
response to stress
cell cycle arrest
negative regulation of cell proliferation
response to heat
positive regulation of autophagy
negative regulation of cell migration
cellular response to UV
regulation of apoptotic process
positive regulation of transcription, DNA-templated
autophagic cell death
cellular response to ethanol
cellular response to hydroperoxide
cellular response to methyl methanesulfonate
cellular oxidant detoxification
regulation of signal transduction by p53 class mediator
positive regulation of apoptotic signaling pathway
regulation of transcription, DNA-templated
autophagy
regulation of autophagy
positive regulation of apoptotic process
