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产品信息
MA5-34751
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JG37-64
抗原
Recombinant protein within Human p53 DINP1 aa 80-188
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Wet ice
RRID
AB_2848659
产品详细信息
Positive Control: SH-SY-5Y, HUVEC, HepG2, Mouse stomach tissue, Human stomach tissue, human liver cancer tissue, human kidney tissue, human pancreas tissue.
靶标信息
A novel p53 inducible gene was identified and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein). p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: p53-dependent damage-inducible nuclear protein 1; p53-inducible p53DINP1; p53DINP1; Stress-induced protein; Tumor protein p53-inducible nuclear protein 1
基因别名: P53DINP1; SIP; Teap; TP53DINP1; TP53INP1; TP53INP1A; TP53INP1B
UniProt ID: (Human) Q96A56
Entrez Gene ID: (Human) 94241
autophagosome assembly
transcription, DNA-templated
apoptotic process
response to stress
cell cycle arrest
negative regulation of cell proliferation
response to heat
positive regulation of autophagy
negative regulation of cell migration
cellular response to UV
regulation of apoptotic process
positive regulation of transcription, DNA-templated
autophagic cell death
cellular response to ethanol
cellular response to hydroperoxide
cellular response to methyl methanesulfonate
cellular oxidant detoxification
regulation of signal transduction by p53 class mediator
positive regulation of apoptotic signaling pathway
