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sfl Antibody (PA5-144403) in WB
Western blot analysis of sfl in recombinant protein using a dilution of 1:2,000. Samples were incubated with sfl polyclonal antibody (Product # PA5-144403). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 33.1 kDa. Observed band size: 34 kDa.
产品信息
PA5-144403
产品规格
种属反应
Fruit fly
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Drosophila melanogaster (Fruit fly) NDST protein (1-172aa)
偶联物
形式
Liquid
浓度
2.032 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_3091671
靶标信息
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in diffusion of morphogen wingless (wg) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis, HSPGs being required for movement of wg morphogens. Required for wg signaling during both embryonic and imaginal disk development. Also required for FGF receptor signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase; CG8339-PA; CG8339-PB; diet-wingless; Glucosaminyl N-deacetylase/N-sulfotransferase; sfl-PA; sfl-PB; Sulfateless
基因别名: CG8339; CT24567; Dmel\CG8339; Dmel_CG8339; dw; l(3)03844; lincRNA.S4253; NDST; Sfl
UniProt ID: (Fruit fly) Q9V3L1
Entrez Gene ID: (Fruit fly) 38736
glycosaminoglycan biosynthetic process
sulfur compound metabolic process
spermatogenesis
segment polarity determination
epithelial cell migration, open tracheal system
imaginal disc-derived wing vein specification
mesoderm migration involved in gastrulation
imaginal disc-derived wing margin morphogenesis
heparan sulfate proteoglycan biosynthetic process
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
Wnt signaling pathway
regulation of imaginal disc growth
