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Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
Von Willebrand factor (vWf) is a series of self-aggregated structures, all derived from common glycoprotein subunits, synthesized in endothelial cells and megakaryocytes. The molecular mass of the monomeric vWf unit is 225 kDa. vWf binds to circulating factor VIIIc (antihemophilic factor), hereby stabilizing the latter thus being an important factor in the normal primary haemostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coagulation Factor VIII; coagulation factor VIII VWF; factor viii related antigen; von Willebrand Disease (vWD); von Willebrand factor; vWF
基因别名: F8VWF; VWD; VWF
UniProt ID: (Human) P04275
Entrez Gene ID: (Human) 7450