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产品信息
PA5-33326
产品规格
种属反应
Dog,
Horse,
Human,
Non-human primate,
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human ADORA3.
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2550709
产品详细信息
Percent identity with other species by BLAST analysis: Human, Monkey, Marmoset, Dolphin, Elephant, Dog, Horse, Pig, Opossum (100%).
靶标信息
Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthesis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNF alpha and blocks the endotoxin CD14 receptor signal transduction pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A3 adenosine receptor; AD026; Adenosine A3-R; Adenosine receptor A3; BA552M11.5; RP11-552M11.7
基因别名: A3AR; ADORA3
UniProt ID: (Human) P0DMS8, (Dog) Q28309
Entrez Gene ID: (Pig) 606753, (Human) 140, (Dog) 403805
