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产品信息
PA5-29718
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Pig,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 316 of Human AKR1B1
偶联物
形式
Liquid
浓度
1.06 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547192
产品详细信息
Recommended positive controls: 293T, A431, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Rat (85%), Dog (91%), Pig (86%), Rabbit (89%), Rhesus Monkey (98%), Bovine (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Aldehyde reductase; aldehyde reductase 1; Aldehyde reductase 1 (low Km aldose reductase) (5.8 kb PstI fragment, probably the functional gene); aldo-keto reductase family 1; Aldo-keto reductase family 1 member B1; aldo-keto reductase family 1, member B1 (aldose reductase); aldo-keto reductase family 1, member B4 (aldose reductase); Aldose reductase; AR; Lii5-2 CTCL tumor antigen; low Km aldose reductase; member B1 (aldose reductase)
基因别名: ADR; AKR1B1; Akr1b3; Akr1b4; ALDR1; ALDRED; Alr; ALR-P-I; ALR2; AR; RATALDRED
UniProt ID: (Human) P15121, (Pig) P80276, (Rat) P07943
Entrez Gene ID: (Human) 231, (Pig) 396816, (Rat) 24192
alditol:NADP+ 1-oxidoreductase activity
aldo-keto reductase (NADP) activity
electron carrier activity
glyceraldehyde oxidoreductase activity
retinal dehydrogenase activity
allyl-alcohol dehydrogenase activity
NADP-retinol dehydrogenase activity
oxidoreductase
reductase
metabolite interconversion enzyme
tissue homeostasis
carbohydrate metabolic process
sorbitol biosynthetic process
C21-steroid hormone biosynthetic process
response to stress
response to water deprivation
naphthalene metabolic process
stress-activated protein kinase signaling cascade
norepinephrine metabolic process
daunorubicin metabolic process
doxorubicin metabolic process
fructose biosynthetic process
positive regulation of JAK-STAT cascade
positive regulation of smooth muscle cell proliferation
oxidation-reduction process
maternal process involved in female pregnancy
cellular response to hydrogen peroxide
inner medullary collecting duct development
response to thyroid hormone
cellular response to methylglyoxal
cellular response to peptide
retinoid metabolic process
retinol metabolic process
monosaccharide metabolic process
response to organic substance
