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Predicted to react with chicken, monkey, mouse and rat based on sequence homology.
Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AKT-interacting protein; Ft1; fused toes homolog; Fused toes protein homolog
基因别名: AKTIP; FT1; FTS
UniProt ID: (Human) Q9H8T0
Entrez Gene ID: (Human) 64400