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ALDH6A1 Antibody (PA5-34691) in IHC (P)
ALDH6A1 Polyclonal Antibody detects ALDH6A1 protein at mitochondria on human liver carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded liver carcinoma. ALDH6A1 Polyclonal Antibody (Product # PA5-34691) dilution: 1:250. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-34691
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 219 and 535 of ALDH6A1 (Uniprot ID#Q02252)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2552043
产品详细信息
Recommended positive controls: HepG2, mouse liver.
Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (86%), Xenopus laevis (86%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: aldehyde dehydrogenase 6 family, member A1; Aldehyde dehydrogenase family 6 member A1; malonate-semialdehyde dehydrogenase; Malonate-semialdehyde dehydrogenase [acylating]; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial; MGC40271; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; MMSDH; testicular tissue protein Li 122
基因别名: 1110038I05Rik; AI314632; ALDH6A1; MMSADHA; MMSDH
UniProt ID: (Human) Q02252, (Mouse) Q9EQ20
Entrez Gene ID: (Human) 4329, (Mouse) 104776
fatty-acyl-CoA binding
aldehyde dehydrogenase (NAD) activity
methylmalonate-semialdehyde dehydrogenase (acylating) activity
thiolester hydrolase activity
malonate-semialdehyde dehydrogenase (acetylating) activity
poly(A) RNA binding
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
dehydrogenase
