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AMH Antibody (PA5-26938) in IHC (P)
Immunohistochemistry analysis of AMH in paraformaldehyde-fixed, paraffin-embedded sections human cerebellum tissue. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH 6). Samples were incubated with AMH polyclonal antibody (Product # PA5-26938) using a dilution of 1:25 for 1 hours at 37°C followed by... View More
产品信息
PA5-26938
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 424-451 amino acids of human AMH
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2544438
靶标信息
Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140 kDa disulfide linked precursor that is cleaved to release the mature 30 kDa homodimer. Originally classified as a fetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AMH; Anti-Muellerian hormone; MIS; Muellerian-inhibiting factor; Muellerian-inhibiting substance; Mullerian inhibiting factor; Mullerian inhibiting substance
基因别名: AMH; MIF; MIS
UniProt ID: (Human) P03971, (Mouse) P27106
Entrez Gene ID: (Human) 268, (Mouse) 11705
preantral ovarian follicle growth
urogenital system development
Mullerian duct regression
cell-cell signaling
gonadal mesoderm development
sex determination
sex differentiation
aging
positive regulation of gene expression
response to organic cyclic compound
response to drug
positive regulation of NF-kappaB transcription factor activity
negative regulation of ovarian follicle development
