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ASS1 Antibody (PA5-18679) in ICC/IF
Immunocytochemistry analysis of ASS1 using ASS1 Polyclonal Antibody (Product # PA5-18679) in paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL).
产品信息
PA5-18679
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (ENPKNQAPPGLYTKTQD) corresponding to the internal amino acids of ASS1 (aa 196-212).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10982596
产品详细信息
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
靶标信息
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Argininosuccinate synthase; argininosuccinate synthetase 1; arginosuccinate synthetase 1; Citrulline--aspartate ligase; citrulline-aspartate ligase; RP11-618A20.2
基因别名: AA408052; ASS; Ass-1; ASS1; ASSA; CTLN1; fold
UniProt ID: (Human) P00966, (Rat) P09034, (Mouse) P16460
Entrez Gene ID: (Human) 445, (Rat) 25698, (Mouse) 11898
urea cycle
citrulline metabolic process
argininosuccinate metabolic process
kidney development
liver development
arginine biosynthetic process
aspartate metabolic process
acute-phase response
midgut development
aging
response to nutrient
response to toxic substance
response to zinc ion
response to mycotoxin
response to amine
response to estradiol
response to lipopolysaccharide
response to drug
response to amino acid
response to peptide hormone
positive regulation of nitric oxide biosynthetic process
response to steroid hormone
response to glucocorticoid
response to growth hormone
diaphragm development
response to fatty acid
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to ammonium ion
cellular response to cAMP
cellular response to interferon-gamma
cellular response to tumor necrosis factor
cellular response to glucagon stimulus
cellular response to oleic acid
cellular response to amine stimulus
cellular response to laminar fluid shear stress
cellular response to dexamethasone stimulus
negative regulation of leukocyte cell-cell adhesion
cellular amino acid biosynthetic process
